مشخصات پژوهش

عنوان	Adapting the release characteristics of aluminum phosphide from membrane-coated rice tablets by using activated carbon nanoparticles
نوع پژوهش	مقاله چاپ‌شده
کلیدواژه‌ها	Membrane-coated tables; Aluminum phosphide; Release characteristic; Activated carbon nanoparticles; Physico-chemical property
چکیده	Membrane-coated tables were prepared to control the release rate of aluminum phosphide from rice tablets when this tablet comes into contact with water in the stomach. Mixed matrix polyvinyl chloride-co-activated carbon nanoparticles (ACNPs) membranes was used as a thin film to coat the rice tablets. The effect of ACNPs as additive in membrane matrix on release behavior of aluminum phosphide was evaluated. The scanning electron microscopy (SEM) images and X-ray diffraction patterns showed that nanoparticles are uniformly distributed in the prepared coatings. The membrane water contact angle was enhanced from 55° to 80° in the presence of ACNPs. The tear resistance of the prepared membranes was also improved from 4.34 to 5.01 (grf/mic) by using ACNPs. The membrane-coated tablets showed a controlled aluminum phosphide release rate compared to pristine rice tablet without cover. The fastest aluminum phosphide release rate for all samples is related to the first five days. In addition, the half-time and life-time of membrane-coated tablets were declined by an increase of the ACNPs ratio up to 15 wt%. Swelling of the fabricated cover in aqueous environment led to a decrease of the aluminum phosphide release rate.
پژوهشگران	علیرضا خدابخشی (نفر ششم به بعد)، حسن صلحی (نفر پنجم)، بارت وندر بروگن (نفر چهارم)، سیدمحسن حسینی (نفر سوم)، الهام جشنی (نفر دوم)، صدرا صلحی (نفر اول)