عنوان
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Mild Synthesis of mono-, bis- and tris 1,2-Dihydrobenzo[4,5]imidazo[1,2- a]pyrimidine Derivatives Using Alkyl Disulfamic Acid Functionalized Magnetic Nanoparticles
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نوع پژوهش
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مقاله چاپشده
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کلیدواژهها
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Nanoparticles, magnetite, heterogeneous catalysis, sulfamic acid, imidazo[1,2-a]pyrimidine, multicomponent reaction
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چکیده
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Alkyl disulfamic acid-functionalized silica-coated magnetic nanoparticles (ADSA-MNPs) have been synthesized as a hybrid organic- inorganic acidic nanoparticles and its catalytic activity has been evaluated in thesynthesis of mono-, bis- and tris 1,2-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine via a one-pot three, pseudo-five or pseudo-seven component condensation reaction of aromatic aldehydes, malononitrile and 2-aminobezimidazole under solvent-free heating. The heterogeneous catalyst was facilely separated from the reaction mixture by utilizingexternal magnetic field and reused for several times without considerable decrease of catalytic performance.
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پژوهشگران
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علیرضا کریمی (نفر سوم)، زهرا فرکی (نفر دوم)، محمد علی بداغی فرد (نفر اول)
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