عنوان
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Nanomolar simultaneous determination of epinephrine and acetaminophen on a glassy carbon electrode coated with a novel Mg–Al layered double hydroxide–nickel hydroxide nanoparticles–multi-walled carbon nanotubes composite
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نوع پژوهش
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مقاله چاپشده
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کلیدواژهها
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Epinephrine, Acetaminophen, Multiwalled Carbon Nanotubes, Nickel Hydroxide Nanoparticles, LDH
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چکیده
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The present work demonstrates that the simultaneous determination of epinephrine (EPI) and acetaminophen (ACT) can be performed using a glassy carbon electrode (GCE) modified with a novel multi-walled carbon nanotubes (MWCNTs), nickel hydroxide nanoparticles (NHNPs) and Mg–Al layered double hydroxide (LDH) composite (MWCNTs–NHNPs–LDH/GCE). The electro-oxidations of EPI and ACT were investigated using cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CA) methods. Under optimum conditions, DPV indicated linear relationships between oxidation peak current and EPI and ACT concentrations in the ranges of 0.04–60 mM and 0.02–40 mM with detection limits of 11 and 5 nM, respectively. The proposed method was successfully applied to the determination of these compounds in human urine and blood serum samples.
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پژوهشگران
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غلام حسن عظیمی (نفر سوم)، محمد افراسیابی (نفر دوم)، علی بابایی (نفر اول)
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