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چکیده
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An efficient, rapid, simple and scalable synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles is shown by condensation reaction of benzil, aldehydes and ammonium acetate/aniline in the presence of deep eutectic solvents as eco-friendly ionic liquid catalysts under solvent-free conditions at 100 C. This approach offers many advantages such as good yield, reduction of waste, short reaction time, easy isolation of products, facile purification and environmentally benign reaction conditions.
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