عنوان
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Silica sulfuric acid magnetic nanoparticle: An efficient and eco-friendly catalyst for synthesis of spiro[2-amino-4H-pyran-oxindole]s
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نوع پژوهش
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مقاله چاپشده
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کلیدواژهها
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magnetic nanoparticles, silica sulfuric acid, spiro[2-amino-4H-pyran-oxindole], isatin,ultrasound irradiation
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چکیده
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Silica sulfuric acid magnetic nanoparticles efficiently catalyze the one-pot, three-component reaction of isatins and malononitrile with dimedone, 1,3-dimethylbarbituric acid or 4-hydroxycoumarin in EtOH-H2O to afford the corresponding spiro[2-amino-4H-pyran-oxindole] derivatives in high yields under ultrasound irradiation at 60 °C. The heterogeneous nanocatalyst could be recovered easily from the reaction mixture using an external magnet and reused many times without significant loss of its catalytic activity.
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پژوهشگران
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مرضیه کریمی (نفر چهارم)، زینب دلیرنسب (نفر سوم)، میثم سوری نیا (نفر دوم)، علیرضا کریمی (نفر اول)
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