In this research (polyvinyl chloride-blend-cellulose acetate/iron oxide nanoparticles) nanocomposite membranes were prepared by casting technique to lead removal from wastewaters. The effect of blend ratio of polymer binder (PVC to CA) and Fe3O4 nanoparticles concentration on physico-chemical characteristics of membranes were studied. Water permeability and ionic rejection tests, water content and mechanical properties measurements and SEM analysis were carried out in membranes characterizations. Obviously, modified membrane containing 10 wt% CA and 0.1 wt% Fe3O4 nanoparticles showed better performance in lead removal compared to other modified membranes and also pristine ones.