2024 : 4 : 14
Mojgan Zendehdel

Mojgan Zendehdel

Academic rank: Professor
ORCID: https://orcid.org/0000-0003-1890-0317
Education: PhD.
ScopusId: 8613426000
Faculty: Science
Address: Arak University


Simultaneous measurement of hydrogen carbonate and acetate anions using biologically active receptor based on azo derivatives of naphthalene
Hydrogen carbonate anion Acetate anion Chemosensor Biological activity
Journal Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Researchers Mojgan Zendehdel ، Saeid Amani Komaei ، Fatemeh Parchegani


A novel receptor based on azo-derivatives of 1-naphthylamine (2-((E)-((4-chloro-3-(trifluoromethyl)phenyl) imino)methyl)-4-((E)-naphthalene-1-yldiazenyl)phenol(2) abbreviated CTNP was successfully designed and synthesized. Its sensing propertieswere studied deeply. Systematic studies of CTNPwith HCO3 − and AcO− anions in DMSO disclosed that there is hydrogen-bonding between CTNP and incoming anions. Significant changes in the visible region of the spectrum, as well as a drastic color change of CTNP from pale yellow to red, observed due to interaction as mentioned earlier. The stoichiometry of [CTNP: HCO3 − or AcO−] complexes and association constants determined through Job'smethod and Benesi-Hildebrand (B-H) plot, respectively. Taking into account the analysis results, CTNP performs the selective recognition of sub-millimolar concentrations of HCO3 − and AcO− efficiently. The antifungal activity of the receptor was tested against Aspergillus brasiliensis and Aspergillus niger. CTNP exhibited excellent antifungal activity against both strains. CTNP also represented antibacterial activity against Gram-positive bacteria: Staphylococcus epidermidis. It was cleared that designed receptor can be applied under physiological conditions for a long duration.