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Mohammad Yaser Masoomi

Mohammad Yaser Masoomi

Academic rank: Assistant Professor
ORCID: https://orcid.org/0000-0003-1329-5947
Education: PhD.
ScopusId: 36927960900
Faculty: Science
Address: Arak University
Phone:

Research

Title
Sensitive Ratiometric Fluorescent Metal-organic Framework Sensor for Calcium Signaling in Human Blood Ionic Concentration Media
Type
JournalPaper
Keywords
ratiometric fluorescent sensor; metal-organic frameworks; Ca2+; sensitivity; selectivity
Year
2020
Journal ACS APPL MATER INTER
DOI
Researchers mino baghery ، Mohammad Yaser Masoomi

Abstract

Two dimensional fluorescent MOF sensor, TMU-5S, was synthesized by introducing Rhodamine B into the framework of TMU-5. This dye sensitized MOF was explored as a ratiometric fluorescent sensor for Ca2+ signaling in presence of interfering cations in ionic concentrations similar to that of blood plasma that exhibits exceptional sensitivity and selectivity to Ca2+ and faster response and recovery times than any other reported fluorescent sensor. This can be attributed to strong electrostatic interactions between basic azine groups in the narrow pore walls of TMU-5S and Ca2+ as hard-hard acid-base interactions. The results show that the two dimensional signal transduction can reduce interfering responses from the environment and thus create exceptional sensitivity.