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Akbar Mobinikhaledi

Akbar Mobinikhaledi

Academic rank: Professor
ORCID: https://orcid.org/0000-0002-9732-7282
Education: PhD.
ScopusId: 6701730547
Faculty: Science
Address: Arak University
Phone:

Research

Title
Microwave-assisted efficient synthesis of azlactone derivatives using 2-aminopyridine-functionalized sphere SiO2 nanoparticles as a reusable heterogeneous catalyst
Type
JournalPaper
Keywords
Nano-sphere silica Azlactone Heterogeneous catalyst Erlenmeyer synthesis Microwave irradiation
Year
2015
Journal Chinese Chemical Letters
DOI
Researchers Akbar Mobinikhaledi ، Hassan Moghanian ، Samira Pakdel

Abstract

In the present work, the highly efficient Erlenmeyer synthesis of azlactones catalyzed by 2- aminopyridine, supported on nano-sphere SiO2 is reported. First, the silica nanoparticles were modified with triethoxysilylpropyl chloride and then 2-aminopyridine was attached to the support via covalent linkages. This new heterogenized catalyst was used for efficient microwave-assisted synthesis of azlactone derivatives with Ac2O as a condensing agent under solvent-free conditions. The present method offers advantages including high yields, short reaction times and simple work-up. Also, the catalyst can be easily recycled and reused several times, which makes this method attractive, economic and environmentally-benign.