عنوان
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MICROWAVE-ASSISTED SOLVENT-FREE SYNTHESIS OF 3,4DIHYDROPYRIMIDIN-2(1H)-ONES CATALYZED BY NH4OBr
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نوع پژوهش
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مقاله چاپشده
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کلیدواژهها
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3,4-Dihydropyrimidin-2(1H)-one; Biginelli-type condensation; Ammonium hypobromite; Aldehydes; β-Keto ester; Urea; Solvent-free; Aromaticity; Asymmetric synthesis; C–C coupling; Heterocycles; Heterogeneous catalysis.
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چکیده
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Catalytic potential of ammonium hypobromite in the one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones from Biginelli-type condensation reaction between an aldehyde, β-keto ester and urea has been explored. The reaction proceeds under solvent-free conventional heating as well as microwave-irradiation conditions to afford the respective products in excellent yields
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پژوهشگران
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زهره نجمی نژاد (نفر چهارم)، خدیجه سلیمانی (نفر سوم)، کاوه خسروی (نفر دوم)، داوود آذری فر (نفر اول)
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