Background & Aim: The purpose of this study was to investigate the effect of 12 concurrent training on prostate specific antigen (PSA), cardiopulmonary endurance, muscular strength and body composition in men over 50 years. Materials and Methods: In this quasi-experimental study, the statistical sample consisted of 29 men with average weight of 81.1± 6.7 kg and body mass index of 26.4 ± 1.4 kg /m2, randomly divided into two control untrained group (N=12) and training group (N=17). The concurrent training group performed concurrent training (endurance-resistance) training for 12 weeks. Serum PSA levels, cardiopulmonary endurance (VO2max), muscle strength, and body compositions were measured before and after training. Data were analyzed using covariance analysis (ANCOVA) (P <0.05). Results: Concurrent training in the training group significantly reduced PSA compared to the control untrained group (P=0.001). As well as training significantly decreased fat mass (P=0.046) and the ratio of waist to hip circumference (P=0.024) also significantly increased cardiorespiratory endurance (VO2max) (P=0.001), mean relative muscle strength (P=0.001) and lean body mass (P=0.001) in the training group compared to the control untrained group. Conclusion: Overall, our findings showed that concurrent training (endurance-resistance) with increased cardiorespiratory endurance, mean muscle strength, and improved body composition decreased serum prostate-specific antigen (PSA) levels in Men over 50 years old.
