Many key rangeland species, particularly in steppe regions, are endangered due to improper land use practices. The loss of these species leads to significant environmental crises [1]. Vitex agnus-castus L., a valuable medicinal plant belonging to the Verbenaceae family, is one such species. In this study, the MaxEnt species distribution model was used to identify the key environmental variables influencing the distribution of this plant [2]. Results indicated that the minimum temperature of the coldest month (31.8%), solar radiation (21.1%), geology (21.1%), soil sand content (13.6%), precipitation in the driest season (12.5%), and isometry (2.1%) are the most important factors affecting its distribution. Vitex agnus-castus shows optimal performance in temperate regions with mild winters and requires a minimum temperature above -5°C. It also depends on moderate solar radiation (~1000 µmol/m²/s) and well-drained sandy soils. Moderate precipitation during the dry season is also essential for its growth. Identifying these factors can aid in selecting suitable regions for the cultivation and sustainable use of this medicinal species.