Flavonoid compounds are taxonomically important. They are popular characters for chemosystematic studies because: the almost universal presence of flavonoids in vascular plants; 2. Their structural diversity; 3. The fact that each species usually contains several flavonoids; 4. The chemical stability of many flavonoids in dried plant material enabling herbarium material to be used; 5. Flavonoid profiles using different chromatographic techniques are easily obtained. 6. Flavonoids ar e reasonably easy to identify using published UV spectra data and available standards; 7. Flavonoids often show correlations with existing classifications at the family, genus and species level, and support revisions of existing classifications at the family, genus and species level. However, flavonoids rarely provide keycharacters The aim of this chpter book was to compare the leaf flavonoids profiles of some Iranian Angiosperm species from Leguminosae, Polygonaceae, Euphorbiaceae, Resedaceae and Cyperaceae.