Around the world due to plant diseases, the amount of crop decreases annually. Different natural and synthetic approaches to manage and reduce damage diseases are used, out of which using nanoparticles is one of them. In the last decades, interest in research on using nanoparticles has increased because of the global concern about environmental pollution. A variety of traditional physical and chemical processes are used to produce nanoscale materials, but nowadays environment-friendly green chemistry-based techniques are available to biologically synthesize materials. Recently, nanotechnology and biology have convergence to create a new field called nanobiotechnology which incorporates the use of biological entities such as actinomycetes, algae, bacteria, fungi, viruses, yeasts, and plants in a number of processes, either biochemical or biophysical. Nanobiotechnology processes have a significant potential to boost nanoparticle production and reduce the use of harsh, toxic, and expensive chemicals that are commonly used in the conventional physical and chemical processes of production.