Introduction: Coronavirus pandemic and the resulting anxiety threatens the physical and mental health of individuals. This study aimed to compare the health-promoting lifestyle dimensions between two groups of students with severe and mild Coronavirus anxiety. Method: Three hundred and Seventy undergraduate students of Arak University participated in this causal-comparative study in the academic year of 2020-2021. The participants were asked to complete two questionnaires of Coronavirus Anxiety and Health-Promoting Lifestyle Profile. Then, the two groups with mild (N = 37) and severe (N = 37) Coronavirus disease anxiety were selected through the screening and convenience sampling method. Finally, the two groups were compared in terms of health-promoting lifestyle dimensions using multivariate analysis of variance. Results: The results concerning the analysis of the variance showed that there is a significant difference between the health-promoting lifestyle of the two groups with mild and severe Coronavirus anxiety. In addition, the group with mild Coronavirus anxiety reported higher spiritual growth compared to the group with severe Coronavirus anxiety. Conclusion: According to the results, it seems that spiritual growth plays a significant role in the management and control of Coronavirus anxiety compared to the other dimensions of health-promoting styles.