1,2-Diphenyl-1,1,2,2-tetrahydroperoxyethane (THPDPE) is a solid and versatile oxidant that is gaining popularity in the field of organic synthesis. Notably, it offers the advantage of being a mild oxidant that can be utilized in solventfree conditions, thus presenting a greener alternative to traditional oxidants like chromium trioxide and permanganate. Moreover, THPDPE exhibits selectivity, enabling the oxidation of specific functional groups while leaving others untouched. This characteristic renders it a valuable tool for organic chemists seeking a versatile and safe oxidant for their reactions. The following summary outlines the most significant reactions accomplished using this reagent:
