We investigate the effect of one loop quantum corrections on the elastic scattering of dark matter off the nucleon in a fermionic dark matter model. The model introduces two new singlet fermions and a singlet scalar. The fermions communicate with the SM particles through a Higgs portal. It is found that some viable regions in the parameter space respecting the bounds from the observed relic density, the Higgs invisible decay width, and direct detection experiment, will be shrunk significantly when one loop effects are taken into account. The regions already resided below the neutrino floor, partly may come into regions which are testable by the current or future direct detection experiments. In addition, some regions being viable at tree level, may be excluded when quantum corrections are included.
