Skyrme Forces (SF) Based Mean Field Model (MFM) or related density function is widely used to describe nuclear states, collective vibrational excitation, and heavy-ion collisions. To investigate 100Sn + 16O and 100Sn + 48Ca collisions on a 3-dimensional(3D) mesh with Skyrme SV-bas forces in Ecm=100, 150, and 200 MeV, Time- Dependent Hartree-Fock Skyrme(TDHFS) computations were done. The effective interaction in the computation of reaction dynamics as an important role in understanding the dynamics of the reaction provides us with knowledge about the characteristics of heavy-ion reactions’ effective interaction. The effect of increasing the ratio of neutrons to protons and the symmetry and asymmetry of the nuclei, as well as the size of the box at different energies, on the structure of the composite core, was investigated. The 100Sn + 16O collision time course findings reveal that the continuous dampening effect remains after the fusion process. The damping mechanism has been demonstrated to be connected to breaking the dependency on box size, which is like the twisted average boundary condition that may avoid box size impacts on the 3D coordinate space employed, whereas periodic boundary conditions are seen for 100Sn + 48Ca.