Cyclones are generally utilized in the industry to separate solid particles from gas streams. A solid–gas taking apart system with a turbulent swirling flow that happens in the cyclone will create erosion on the cyclone wall. The erosion will make a fall in cyclone effectiveness and augment the upholding cost. In this examination, the modeling of erosion produced by solid particles in cyclones of a new design for gas–solid two-phase dense flow along with two-way and four-way coupling effects was done using computational fluid dynamics. The effect of fluid flow velocity parameters, inlet particle diameters, and solid loading at the erosion rate (ER) was discussed. The distribution of pressure contours, axial velocity, and tangential velocity were compared in all couplings. Reynolds stress turbulence model was utilized to solve the flow equation. The DDPM-KTGF technique was used to calculate the particle–particle interactions in the dense discrete phase, and the erosion prediction was assessed by using the Oka model. The outcomes show that the ER rises with the rise in the velocity and diameters of the particles, but the rise in the solid loading ratio in the four-way coupling forecasts the erosion reduction. The cushioning efficacy promoted by inter-particle collisions reduces the ER.