In this paper, numerical study of flow field in the new design cyclones with five different wall temperature profiles are investigated. The new design cyclone is based on the idea of improving cyclone collection efficiency and pressure drop by increasing the vortex length. In this paper, the five wall temperature profiles are as follows: (A) cooling with uniform distribution, (B) without temperature change, (C) heating with uniform distribution, (D) incremental linear heating, (E) reduction linear heating. Results are compared in new design and conventional cyclones. The Reynolds averaged Navier–Stokes equations with Reynolds stress turbulence model (RSM) are solved. The Eulerian-Lagrangian computational procedure is used to predict particles tracking in the cyclones. The velocity fluctuations are simulated using the Discrete Random Walk (DRW). Results show that generally, heating the bottom zone of the cyclones can improve the collection efficiency and reduce the pressure drop while heating the top zone of the cyclones marginally affects the flow field. Moreover, cooling the cyclones reduces the efficiency and causes a higher pressure drop. Among five different wall temperature profiles, C and E profiles can increase the efficiency about 8% and profile C reduces the pressure drop by about 9%. The mentioned values in different conditions including particle diameter, flow rate, etc. can be different.