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Gholamreza Nabiyouni

Gholamreza Nabiyouni

Academic rank: Professor
ORCID: https://orcid.org/0000-0001-8703-9693
Education: PhD.
ScopusId: 6602215199
HIndex:
Faculty: Science
Address: Arak University
Phone:

Research

Title
Magnetic Fe3O4@Poly Vinyl Alcohol@Vitamin C Nanocomposite and Its Application in Gradually Drug Release
Type
JournalPaper
Keywords
Drug release, Iron oxide, Nanocomposite, Polyvinyl alcohol, Vitamin C.
Year
2024
Journal Journal of Nanostructures
DOI
Researchers shokofeh sabaghi karahrodi ، Gholamreza Nabiyouni ، Ziba Sorinezami ، Davood Ghanbari

Abstract

In recent years, the use of nanoparticles in the field of medicine has attracted many attentions. The surface coating of nanoparticles by biocompatible polymers improves their bioavailability. Due to the compatibility of bio-polymers with the environment and human body, these materials are used as carrier agents. In this research, magnetic nanoparticles were synthesized by microwave and hydrothermal methods. The iron oxide nanoparticles (Fe3O4) were coated with polyvinyl alcohol (PVA) to prepare nanocomposite and load the drug (vitamin C) from the mechanical agitator. The nanoparticles crystal structure was studied using X-ray diffraction (XRD). The nanoparticles size was determined by scanning electron microscopy (SEM). Vibrating sample magnetometer (VSM) was used for magnetic analysis, and the purity of the material was determined by applying Fourier transform infrared spectrometer (FT-IR). Evaluation of drug release was investigated by ultra violet-visible (UV-Vis) spectroscopy.