Abstract: Objective ― The purpose of this study was to investigate the effect of cognitive and exercise rehabilitation training, and noninvasive brain stimulation on the gait of schizophrenic patients suffering from depression disorder. Methods ― Fifty-five male schizophrenic patients suffering from depression disorder aged 24 to 66 years were assigned to either a control group (n=10), cognitive rehabilitation group (n=10), exercise rehabilitation training group (n=13), transcranial direct current stimulation (tDCS) group (n=11) or multimodal intervention group (n=11). Gait was measured using a 10-meter gait speed test under normal, in dualtask cognitive-gait, and in dual task motor-gait conditions. Results ― Gait speed during the 10-meter walk test under normal conditions was significantly (P≤0.05) different from pre- to post-test in the exercise rehabilitation training, and cognitive rehabilitation multimodal intervention. Gait speed during the dual task motor-gait condition was significantly different from pre- to post-test in the exercise rehabilitation training, cognitive rehabilitation and, multimodal intervention groups (P≤0.05). Gait speed during the dual task cognitive-gait condition significantly changed from pre- to post-test following exercise rehabilitation training, cognitive rehabilitation, tDCS and the multimodal intervention group (P≤0.05). Conclusion ― This study’s findings demonstrate that exercise rehabilitation training, cognitive rehabilitation, and multimodal interventions could assist with preventing falls within Schizophrenic patients suffering from depression and thereby improve their functional independence.
