In this study, a green and environmentally friendly catalyst (MgZnFe2O4@ZSC-Cu) was synthesized using a simple and clean method. The catalyst was prepared by combining MgZnFe2O4 MNPs with Ziziphus spina-christi extract (ZSC) and immobilizing Cu ions on the resulting material. The catalyst was thoroughly characterized using various techniques including Fouriertransform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), Field emission-scanning electron microscopy (FE-SEM), Energy dispersive X-ray analyzer (EDS), Inductively coupled plasmaoptical emission spectrometry (ICP-OES), Thermogravimetric (TGA), and Vibrating sample magnetometry (VSM) analyses. The catalytic activity of MgZnFe2O4@ZSC-Cu was evaluated in the Hantzsch reaction involving a four-component reaction with ethyl acetoacetate or dimedone/ cyclohexane-1,3-dione, various aromatic aldehydes/di-aldehydes, and ammonium acetate. The structure of the newly formed bis compound and polyhydroquinolines was determined using FTIR, 1 H and 13C NMR spectroscopy. This catalyst provides numerous benefits, such as simple separation using a magnet, less reaction times, high product yield, solvent-free conditions, straightforward work-up, and the capability to reuse the catalyst for up to five cycles.
