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Akbar Mobinikhaledi

Akbar Mobinikhaledi

Academic rank: Professor
ORCID: https://orcid.org/0000-0002-9732-7282
Education: PhD.
ScopusId: 6701730547
HIndex:
Faculty: Science
Address: Arak University
Phone:

Research

Title
Synthesis of some 4H-pyran derivatives using bio-synthesized ZnO nanoparticles and the evaluation of their biological activities
Type
JournalPaper
Keywords
ZnO, 4H-pyrans, Catalyst, Malononitrile, Ficus carica leaves
Year
2021
Journal Org. Chem. Res
DOI
Researchers Akbar Mobinikhaledi ، Seyyed Mehdi Shariatzadeh ، Hassan Moghanian ، Majid Komijani ، javad ghanbariyan

Abstract

ZnO Nanoparticles were simply synthesized by green biosynthesis method using ficus carica leaf extract. The structure of these nanoparticles was assigned using Fourier transform infrared spectroscopy (IR), Field emission-scanning electron microscopy (FE-SEM), and X-ray powder diffraction (XRD). The catalytic activity of these nanoparticles was studied for the synthesis of 4H-pyrans. A series of 4Hpyrans 3(a-l) were synthesized in good to high yields by reaction of corresponding α,α′-bis(substituted benzylidene) cycloalkanones and malononitrile in the presence of ZnO nanoparticles as a catalyst at 110 °C. This environmentally friendly method has some advantages such as high efficiency, use of available catalyst, solvent-free reaction conditions, and easy operation. The antibacterial activity of synthesized 4H-pyrans was also tested using Staphylococcus aureus and Escherichia coli bacterial strains.