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Saeid Amani Komaei

Saeid Amani Komaei

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Science
Address: Arak University
Phone:

Research

Title
Simultaneous measurement of hydrogen carbonate and acetate anions using biologically active receptor based on azo derivatives of naphthalene
Type
JournalPaper
Keywords
Keywords: Hydrogen carbonate anion Acetate anion Chemosensor Biological activity
Year
2020
Journal Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
DOI
Researchers Fatemeh Parchegani ، Masoumeh Orojloo ، Mojgan Zendehdel ، Saeid Amani Komaei

Abstract

A novel receptor based on azo-derivatives of 1-naphthylamine (2-((E)-((4-chloro-3-(trifluoromethyl)phenyl) imino)methyl)-4-((E)-naphthalene-1-yldiazenyl)phenol(2) abbreviated CTNP was successfully designed and synthesized. Its sensing propertieswere studied deeply. Systematic studies of CTNPwith HCO3 − and AcO− anions in DMSO disclosed that there is hydrogen-bonding between CTNP and incoming anions. Significant changes in the visible region of the spectrum, as well as a drastic color change of CTNP from pale yellow to red, observed due to interaction as mentioned earlier. The stoichiometry of [CTNP: HCO3 − or AcO−] complexes and association constants determined through Job'smethod and Benesi-Hildebrand (B-H) plot, respectively. Taking into account the analysis results, CTNP performs the selective recognition of sub-millimolar concentrations of HCO3 − and AcO− efficiently. The antifungal activity of the receptor was tested against Aspergillus brasiliensis and Aspergillus niger. CTNP exhibited excellent antifungal activity against both strains. CTNP also represented antibacterial activity against Gram-positive bacteria: Staphylococcus epidermidis. It was cleared that designed receptor can be applied under physiological conditions for a long duration