Medlar (Mespilus germanica L.) from Rosaceae family is a spiny shrub with 2-3m height in wild and 4-6 m when cultivated [1,2]. Medlar fruit and leaves are extremely rich sources of vitamin C and minerals (Potassium, Sodium, Calcium, Magnesium, Iron), antioxidants and flavonoids [2,3]. Many flavonoids are active principles of medicinal plants, exhibit pharmacological effects and contribute to human health [4]. Contents of sugars (fructose, glucose and sucrose), the main fatty acids (linoleic and palmitic acid), organic acids such as malic and citric acid, aspartate, glutamate and amino acids were determined in high levels in the mature medlar fruits [2]. Main flavonoid in Medlar leaf and fruit is Quercetin, maximum flavonoid content was recorded in their methanolic and aqueous extracts [1]. In this study leaf flavonoids of Mespilus germanica are reported using 2-dimentional paper (2-DPC) and thin layer chromatography (TLC). Results showed M. germanica leaf contain flavonoid sulphates, flavones C and C-/O glycosides. Aglycones was not found. Chrysin, Kaempferol, Myercetin, Quercetin and Rutin were found in the species leaf.
