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Mohammad Ali Bodaghifard

Mohammad Ali Bodaghifard

Academic rank: Associate Professor
ORCID: https://orcid.org/0000-0001-9732-4746
Education: PhD.
ScopusId: 6507703429
Faculty: Science
Address: Arak University
Phone:

Research

Title
MNPs-TBAN as a Novel Basic Nanostructure and Efficient Promoter for the Synthesis of Pyranopyrimidinones
Type
JournalPaper
Keywords
Hybrid nanomaterial, Magnetite, Heterogeneous catalysis, Multicomponent reaction, Pyrano[2,3-d]pyrimidine
Year
2020
Journal ORGANIC CHEMISTRY RESEARCH
DOI
Researchers Elham Khalili ، Mohammad Ali Bodaghifard ، NAJMIEH AHADI

Abstract

In this study, magnetite nanoparticles (Fe3O4) were synthesized as a magnetic core by chemical co-precipitation process and coated with a silica layer. The (Fe3O4@SiO2) core-shell magnetic nanoparticles were functionalized by organic-base tags to produce the MNPs-TBAN nanoparticles as a novel hybrid nanostructure. The morphology, stability, and magnetism of this hybrid nanostructure were characterized and studied by Fourier transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TGA), vibrating sample magnetometry (VSM), X-ray powder diffraction analysis (XRD), scanning electron microscopy (FE-SEM), and transmission electron microscopy (TEM). The prepared hybrid nanomaterial was successfully used as a basic heterogeneous catalyst for the synthesis of pyrano[2,3-d]pyrimidine derivatives, via the condensation of an aldehyde, malononitrile and barbituric acid or thiobarbituric acid. The reaction was afforded the desired products in high purity and has advantages of excellent yields, simple workup procedure, and short reaction time. The catalyst was easily separated from the reaction mixture with the assistance of an external magnet and reused for several runs without noticeable deterioration in catalytic activity.