2024 : 4 : 14
Mohammad Ali Bodaghifard

Mohammad Ali Bodaghifard

Academic rank: Associate Professor
ORCID: https://orcid.org/0000-0001-9732-4746
Education: PhD.
ScopusId: 6507703429
Faculty: Science
Address: Arak University


Bis sulfamic acid-functionalized nanocatalyst as an efficient and retrievable catalyst for synthesis of 1,4-dihydropyridines
nanocatalyst, Synthesis
Researchers Mohammad Ali Bodaghifard


As one of the known MCRs, Hantzsch reaction has attracted much attention on the synthesis of 1,4-dihydropyridines (1,4-DHPs) due to their significant biological and pharmacological properties such as antitubercular ,anticonvulsant, antitumour ,analgesic, antiinflammatory and stress protective activities [1]. Hybrids of organic-inorganic materials are of great interest as heterogeneous catalysts in organic synthesis, since the functionality and flexibility of organic moiety as well as thermal and structural stability of inorganic solids are collected in these systems [2]. Their large surface area per unit volume, a consequence of their small diameter, makes them interesting in the area of heterogeneous catalysis; Heterogeneous catalysis in the nano-scale takes advantage of a high exposure of the active species leading to a higher efficiency of the catalyst [3]. Considering the importance of MCRs and the diverse applications of 1,4-DHPs and the limitation with the previous synthetic routes and our earlier interest in green procedures of MCRs and recyclable organic-inorganic nanocatalysts [4], we wish to report an efficient and convenient methodology for the Hantzsch reaction by one-pot cyclocondensation of aldehydes, ammonium acetate and ethylacetoacetate under mild and green conditions