The production and release of nanoparticles and their impacts on living organisms are among the most important concerns in the world. Spirulina platensis was chosen because of its ability to absorb more elements than other algae. Therefore, an experiment was conducted to improve the product quality of spirulina exposed to new type of nanoparticles. In this experiment, vanadium oxide nanoparticles (VNPs) and tungsten oxide nanoparticles (WNPs) were used at concentrations of 0, 0.001, 0.017, and 0.05 g/l. The measured indices such as protein percentage and concentrations of phycobiliproteins and carbohydrates were the most important parameters of spirulina. Results showed that the concentration of 0.001 g/l of VNPs signifcantly afected the amounts of protein and phycocyanin. It has also been observed that 0.001 g/l of WNPs signifcantly infuenced the amounts of protein (5.3%) and phycocyanin (90%); however, WNPs at all concentrations increased the concentrations of protein and phycocyanin. A concentration of 0.05 g/l of WNPs increased phycocyanin content by 83% over the control. The examination of nanoparticles by spirulina showed that VNPs were more adsorbed by spirulina than WNPs. In general, VNPs were toxic to algae at concentrations of 0.017 and 0.05 g/l, but WNPs did not show any fatal toxicity
