2024 : 4 : 16
Kaveh Khosravi

Kaveh Khosravi

Academic rank: Associate Professor
ORCID: https://orcid.org/0000-0002-5671-944X
Education: PhD.
ScopusId: 26648894200
Faculty: Science
Address: Arak University


Antimony (III) chloride as an effective catalyst for conversion of aldehydes and ketones to corresponding gem-dihydroperoxides
SbCl3, gem-dihydroperoxide, Hydrogen peroxide , aldehydes, ketones
Researchers Davood Azarifar ، Kaveh Khosravi ، Boshra Mahmoudi


Gem-dihydroperoxides which have been much important in recent years due to their relevance to peroxidic anti-malarial drugs are stable derivatives of aldehydes and ketones [1]. These compounds are useful and vital key intermediates in synthesis of many classes of peroxides, such as tetraoxanes [1] and other tetraoxacycloalkanes, [2] macrocyclic endoperoxides, [3] and acyclic analogues with a variety of functional groups [4]. In addition, recently gem-dihydroperoxides have been used as suitable and powerful oxidant in some organic reactions [4]. In this research, we have used antimony (III) chloride (SbCl ) as a new, efficient and commercially available simple catalyst for conversion of different aldehyde and ketones to corresponding gem-dihydroperoxides in high yields and purity (scheme 1). Time of reactions are short to moderate. Finally, it seems that conditions of reactions are mild and methods of purifications are simple.3