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Farzad Bamdad

Farzad Bamdad

Academic rank: Associate Professor
ORCID: https://orcid.org/0000-0002-3900-0783
Education: PhD.
ScopusId: 23487653700
Faculty: Science
Address: Arak University
Phone:

Research

Title
Spectrophotometric determiation of L-cysteine by using polyvinylpyrrolidone-stabilized silver nanoparticles in the presence of barium ions
Type
JournalPaper
Keywords
Silver nanoparticles,Cystein,Aggregation,Human plasma,Surface plasmon
Year
2016
Journal Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
DOI
Researchers fateme Khorram ، Farzad Bamdad ، Maryam Samet ، Kourosh Bamdad ، Mohammadreza Sangi ، fateme Allahbakhshi

Abstract

In this article a simple and selective colorimetric probe for cysteine determination using silver nano particles (AgNPS) is described. The determination process was based upon the surface plasmon resonance properties of polyvinylpyrrolidone-stabilized AgNPS. Interaction of AgNPS with cysteine molecules in the presence of barium ions induced a red shift in the surface plasmon resonance (SPR) maximum of AgNPs, as a result of nanoparticle aggregation. Consequently, yellow color of AgNP solution was changed to pink. The linear range for the determination of cysteine was 3.2-8.2μM (R=0.9965) with a limit of detection equal to 2.8μM (3σ). The proposed method was successfully applied to the determination of cysteine in human plasma samples. Acceptable recovery results of the spiked samples confirmed the validity of the proposed method.