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Alireza Salabat

Alireza Salabat

Academic rank: Professor
ORCID: https://orcid.org/0000-0003-3364-4200
Education: PhD.
ScopusId: 6603263297
Faculty: Science
Address: Arak University
Phone:

Research

Title
Design of new Quercetin- loaded microemulsion formulation: phase diagram, solubility and stability investigations
Type
Presentation
Keywords
quercetinو solubility
Year
2016
Researchers Azar Kajbafvala ، Alireza Salabat

Abstract

The aim of this study was to developing a new formulation for quercetin that is an antioxidant drug with very poor water solubility [1]. For this goal, pseudo ternary phase diagrams were constructed to obtain microemulsion areas which had mono-phasic nature and very good thermodynamic stability [2]. Between microemulsion regions, some formulations composed of clear amounts of surfactant, cosurfactant, oil and water were chosen. Then quercetin was incorporated in w/o microemulsions, and solubility of drug was probed in each formulation. Results showed that inclusion of quercetin into w/o microemulsions caused to very good increment in drug solubility values (in comparison to its solubility in water). These outcomes were very practical in drug delivery applications of quercetin.