2024 : 4 : 19
Alireza Salabat

Alireza Salabat

Academic rank: Professor
ORCID: https://orcid.org/0000-0003-3364-4200
Education: PhD.
ScopusId: 6603263297
Faculty: Science
Address: Arak University
Phone:

Research

Title
IN VITRO RELEASE BEHAVIOR AND EX VIVO EVALUATION OF QUERCETIN-MICROEMULSIONS FOR TOPICAL DELIVERY
Type
Presentation
Keywords
Microemulsion, drug delivery, Quercetin
Year
2016
Researchers Azar Kajbafvala ، Alireza Salabat

Abstract

This work was aimed for developing release behaviour, release kinetics and mechanisms as well as evaluation of ex vivo drug penetration for delivery of the anti-oxidant drug named quercetin encapsulated in microemulsion formulations composed of Tween 80 as surfactant, Transcutol® P as co-surfactant, oleic acid as oil phase and water as aqueous phase. The obtained results showed a slow release behavior without any transdermal delivery. Most of the formulations fitted best with zero-order kinetics and had non-Fickian dissolution mechanisms that could be worthwhile for topical administrations. This study illustrated that the proposed QU-microemulsion formulation has a good potential for use in sunscreen formulations.