Today, one of the major goals in nanotechnology is the development of environmentally friendly products. The use of plants and fruits to synthesize nanoparticles is one of the most environmentally friendly methods for not using pollutants and toxic substances. In this work, the synthesis of zinc oxide (ZnO) nanoparticles is green and were synthesized according to a literature method [1,2] using apple juice. The combination of zinc oxide nanoparticles with multi-wall carbon nanotubes was used to modify the surface of the electrode and construct a new sensor for determination of Paracetamol (PAR). PAR is a long-established substance being one of the most extensively employed drugs in the world [3]. The experimental results suggest that a new electrode (MWCNTs/ZONPs), accelerates the electron transfer reactions of Paracetamol. The DPV data showed that the obtained anodic peak currents were linearly dependent on the Paracetamol concentrations in the range of 0.5–478 mol L−1 in 0.1M phosphate buffer solution at pH 7 with a correlation coefficient of 0.9911. The interfering study of some species showed no significant interference with determination of PAR a wide linear range, low detection limit, high stability and good reproducibility suggest that this electrode will be an attractive candidate for practical applications.
