2024 : 4 : 14
Ali Babaei

Ali Babaei

Academic rank: Professor
ORCID: https://orcid.org/0000-0001-5442-8123
Education: PhD.
ScopusId: 56496577600
Faculty: Science
Address: Arak University


Nanomolar simultaneous determination of levodopa and serotonin at a novel carbon ionic liquid electrode modified with Co(OH)2 nanoparticles and multi-walled carbon nanotubes
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Journal Electrochimica Acta
Researchers Ali Babaei ، Ali Reza Taheri ، Majid Aminikhah


A novel modified carbon ionic liquid electrode is prepared as an electrochemical sensor for simultaneous determination of levodopa (l-dopa) and serotonin (5-HT). The experimental results suggest that a carbon ionic liquid electrode modified with multi-walled carbon nanotubes and cobalt hydroxide nanoparticles, and coated with Nafion (Nafion/Co(OH)2–MWCNTs/CILE), accelerates the electron transfer reactions of l-dopa and 5-HT. In addition it shows no significant interferences of uric acid and ascorbic acid as electroactive coexistent compounds with l-dopa and 5-HT in biological systems. The fabricated sensor revealed some advantages such as convenient preparation, good stability and high sensitivity toward 5-HT and l-dopa determination. The DPV data showed that the obtained anodic peak currents were linearly dependent on thel-dopa and 5-HT concentrations in the range of 0.25–225 and 0.05–75 μmol L−1, respectively. The applicability of the modified electrode was demonstrated by simultaneous determination of 5-HT and l-dopa in human serum.