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Akbar Mobinikhaledi

Akbar Mobinikhaledi

Academic rank: Professor
ORCID: https://orcid.org/0000-0002-9732-7282
Education: PhD.
ScopusId: 6701730547
HIndex:
Faculty: Science
Address: Arak University
Phone:

Research

Title
Synthesis, characterization and antimicrobial activities of some novel bis-chalcones
Type
JournalPaper
Keywords
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Year
2012
Journal Medicinal Chemistry Research
DOI
Researchers Akbar Mobinikhaledi ، Mehdi Kalhor ، Hossein Jamalifar

Abstract

A series of novel bis-chalcones 3a–n were synthesized in excellent yields by condensation reaction of 1,4-diacetylbenzene with various aldehydes in ethanol 96% and aqueous NaOH at room temperature. All compounds were characterized by IR, 1H and 13C NMR, UV spectroscopy and elemental analysis. The antimicrobial activities of synthesized compounds were also evaluated. The most of these compounds exhibited a good activity against Staphylococcus aureus, Escherichia coli and Candida albicans microorganisms. Some of them showed significant activities.